Lactic acid metabolism in the isolated heart (heart lung preparation)
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چکیده
منابع مشابه
Metabolism in Isolated Rabbit Heart
To investigate whether energy derived from glycolytic and oxidative metabolism are preferentially used for different functions in heart, tension, intracellular potential, and extracellular [K+] and pH (using triple barrel K/pH electrodes, tip diameter 0.5 mm) were monitored in isolated arterially perfused rabbit interventricular septa during exposure to hypoxia and metabolic inhibitors. Myocard...
متن کاملThe peripheral circulation and lactic acid metabolism in heart, or cardiovascular, failure.
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The effect of mono(2-ethylhexyl)phthalate on an isolated perfused rat heart-lung preparation.
Di(2-ethylhexyl)phthalate (DEHP), the plasticizer used in the biomedical production of blood storage bags, hemodialysis systems, cardiopulmonary bypass (CPB) circuitry, and intubation tubes, is extracted from the plastic material when it comes into contact with biological fluids and is converted to its principal metabolite, mono(2-ethylhexyl)phthalate (MEHP). We have shown that MEHP causes card...
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Receptor-stimulated phosphatidylinositol turnover has been studied in isolated, perfused, [3H]inositol-labelled rat hearts by measuring accumulation of inositol phosphates in the presence of lithium chloride. Inositol phosphate accumulation was stimulated by norepinephrine (3 X 10(-5) M) and carbachol (10(-3) M), the increases averaging from 931 +/- 59 (n = 6, mean +/- SEM, cpm/g heart) to 4,16...
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Experimental cardiac failure was reinvestigated in tlie completely isolated mammalian heart using a simplified system in which only the left ventricle performs work and exhibits volume changes. An effort was made to assess the importance of such experimental artefacts as acapnia, altered or depleted substrate, and controlled (constant) diastolic volume. None of these factors appeared to play a ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1916
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1916.sp001757